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Mesothelioma and Non Asbestos Exposure The majority of mesothelioma cases occur on the lung linings as well as the abdomen. The rare cancer may also develop in the lining of the heart (pericardium) or in the testes. Asbestos exposure is the main risk factor for mesothelioma. However, some patients diagnosed with mesothelioma may not have an asbestos-related history. Exposure to Asbestos Asbestos is a mineral that is natural that was once employed in industrial and construction products all over the world. People who worked in asbestos-related industries handled the material on a regular basis which put them at risk of exposure. Asbestos fibres can become lodged in the lungs, causing progressive lung disease. This is referred to as asbestosis. Over time, the fibers that are trapped in the lungs may cause mesothelioma. Asbestos is also inhaled or ingested, and the risk of mesothelioma and other asbestos-related illnesses increases with the length and quantity of exposure. Most cases of mesothelioma stem from exposure to occupational toxins. Asbestos is widely used in professions, including electrical work, and maintenance of automobiles. These trades are typically predominantly male-dominated, and as a result, male mesothelioma cases comprise 75-80 percent of all cases reported. The elimination of asbestos in the United States, and other first-world nations, has reduced occupational contamination. This has led to an increase in cases and asbestos exposure outside of the workplace becoming more frequent. Non-occupational Mesothelioma is caused when asbestos is released at the workplace, or is found at home or in schools. The secondhand exposure can also trigger it, such as when a family members touches the clothing of an asbestos worker. The people who suffer from this type of exposure may have symptoms like breathing problems or chest pain that is often mistaken as lung or heart problems. Some studies have linked mesothelioma with non-occupational exposure, however the results are different. A majority of these studies were conducted on a small sample size, and between-study the degree of heterogeneity is high. It is imperative to conduct more studies to confirm the link between asbestos exposure in non-occupational settings and mesothelioma. Anyone who has been exposed to non-occupational exposure should discuss their asbestos history with their physician. If they are concerned, they should ask for a mesothelioma test and a referral to a specialist. Mesothelioma specialists can offer patients the best care and treatment options to improve their chances of survival. They will review medical records, and carry out imaging tests to determine the disease. They will also offer advice on how to file a mesothelioma lawsuit to receive compensation from an asbestos trust fund. Secondhand Exposure While asbestos exposure is the main cause of mesothelioma not the only way to develop this cancer. In phoenix asbestos attorney , there's a small amount of evidence that people can get mesothelioma, even if they have never directly handled asbestos or worked in an industry that involved asbestos-related activities. This is known as secondary or non-occupational asbestos exposure. Asbestos fibers are extremely tiny and can stick to hair, clothing and skin. Workers can carry harmful fibers in their work clothing home and pass them on to family members. These asbestos fibers could be swallowed or inhaled, leading to mesothelioma. This mesothelioma type occurs more often in women and usually in the lung. It can also affect the chest wall or abdomen. The most frequent sign is a shortness of breath (dyspnea) and it is often associated with other symptoms such as fluid in the lungs, or a swelling in the scrotum. The mesothelioma that develops in the lungs is referred to as pleural mesothelioma. Peritoneal mesothelioma is the term used for mesothelioma which affects the stomach wall or chest wall. This kind of mesothelioma could cause a number of symptoms like abdominal pain, difficulty in breathing, and constipation. According to numerous studies, those who have never been exposed to asbestos at work can still develop mesothelioma due to exposure through secondhand sources. These individuals typically lived with someone who had been exposed to asbestos. They could have handled the worker's clothing or had other exposure to asbestos. Veterans are at a higher risk of mesothelioma because asbestos was extensively used in military bases vessels, vehicles and bases. The Navy is especially at risk due to asbestos being used to insulate the hull of the ship and to fireproof gun turrets. Asbestos was also often taken home by sailors after their work aboard ships that had been contaminated. Environmental Exposure A variety of substances have been linked to mesothelioma. The disease is still most often associated with asbestos exposure. Asbestos is a mineral that occurs naturally was used in the manufacturing process for a number of years. The mineral is heat-resistant and strong making it ideal for insulation, brakes, flooring, shingles and other items. When asbestos is broken, it creates dust which can be inhaled or swallowed. These fibers can remain in the lungs or stomach for years, and trigger mesothelioma symptoms. The most frequently reported mesothelioma symptoms are difficulty breathing, chest pain and abdominal discomfort. Asbestos exposure can cause these symptoms to persist for up to 60 years. It is essential to consult your doctor if you notice these symptoms. It is also critical to inform your doctor of your history with asbestos. This will help avoid an incorrect diagnosis and ensure that you receive the appropriate treatment. The most commonly affected mesothelioma victims from asbestos exposure are those who been directly exposed to asbestos but it is possible for loved family members to be affected. This is referred to as secondary exposure. Family members can inhale or ingest asbestos fibers from the work clothing, shoes or other tools. They may be exposed to asbestos by someone who brings home these particles on their clothing or hair. This is why mesothelioma patients and their families must take care to wash their clothing properly after working around asbestos. There is a huge collection of research demonstrating an association between nonasbestos and mesothelioma. However, there are still no definitive conclusions regarding the role played by other agents. For instance there is evidence that the zeolites erionite and chlorosotile can cause mesothelioma. Erionite can be found in soil and rocks from certain areas in Turkey where the risk of mesothelioma pleural is high. The research on the relationship between nonasbestos and mesothelioma is ongoing. Funnel plots have shown the potential for bias in publication, and between-study heterogeneity is high. It is clear that asbestos exposure is the main mesothelioma risk factor. Genetics The mesothelioma-related rare disease occurs when malignant cells in mesothelium multiply uncontrollably and invade surrounding tissues. It can also spread throughout the body traversing the bloodstream or lymphatic system and impacting other organs. Asbestos is the most common cause, but it is not the only cause. The condition could be caused by other environmental and genetic factors. Certain cases of mesothelioma have been reported in people who were not exposed directly themselves to asbestos. They are known as non-occupational mesothelioma patients. They were usually exposed through the handling of harmful household items or clothing by anyone who was exposed to asbestos in their home. For example, it is possible for someone to be diagnosed with pleural mesothelioma based on the exposure to asbestos fibers in clothing belonging to a loved one. Studies show that this type of mesothelioma has longer time to develop and is more likely to be found in women than males. Scientists are currently investigating the possibility that a genetic predisposition to mesothelioma might play a role in the development of the disease. Recent studies have demonstrated that the mutation in the gene BAP1 increases the risk of mesothelioma in asbestos-exposed people. This finding is important because it could lead to improved screening procedures for people who are at high risk of developing mesothelioma. Researchers have discovered that a variety of genes are linked to mesothelioma. These genes are frequently altered in mesothelioma and inhibit the growth of tumors. These genes include the large homolog 2 of tumor suppressor (LATS2) and the NF2. People with mesothelioma-related family history are at a higher risk of developing the disease. This is because some genes, such as the BAP1, can be inherited from an individual parent. Veterans have the highest mesothelioma rate when compared to other occupational categories because asbestos was heavily used in the military. People who were in the Navy and on ships were at greatest risk because of the extensive exposure to asbestos in fireproofing, insulation materials, and shipbuilding.